Embarking on a cruise to South America is a captivating voyage that promises a seamless blend of luxury and exploration. These cruises allow travelers to navigate the continent's diverse coastal wonders, offering a unique perspective on its iconic landmarks and hidden gems. Whether sailing along the Brazilian coast with its lively beach cities, exploring the fjords of Chile and Argentina, or navigating the historic waters around the Galápagos Islands, each itinerary is carefully curated to showcase the best of South America. Onboard amenities and curated shore excursions provide passengers with opportunities to immerse themselves in local cultures, savor exotic cuisines, and witness the natural beauty that defines this extraordinary part of the world. With the comfort of a floating sanctuary and the thrill of discovering new landscapes each day, a cruise to South America is a voyage that promises to create indelible memories for every traveler.

South America Itineraries

11 Nights

Bridge To Mexico

Cruise Line Oceania Cruises
Cruise Type Ocean
Ship Regatta
Region South America
Departure Port Los Angeles, California
Destination Port Los Angeles, California
Itinerary
Los Angeles, California, San Diego, California, La Paz, Mazatlán, Manzanillo, Mexico, Puerto Vallarta, Cabo San Lucas, Ensenada and Los Angeles, California

From Please Call

Plus substantial savings from Deluxe Cruises

Departure Date
20 Apr 24
14 Nights

Peru and the Galapagos Islands

Cruise Line Tauck
Cruise Type Ocean
Ship Isabela II
Region South America
Departure Port Santa Cruz Island, Galápagos
Destination Port Baltra Island, Galápagos
Itinerary
Santa Cruz Island, Galápagos, Lima, Cusco, Machu Picchu, Machu Picchu, Cusco, Baltra Island, Galápagos, Santa Cruz Island, Galápagos, San Cristóbal Island, Galápagos, Espanola Island, Floreana Island, Galapagos, Punta Moreno, Isabella Island, Galapagos, El Edén Island, Galápagos, Baltra Island, Galápagos and Baltra Island, Galápagos

From £11,350pp

Plus substantial savings from Deluxe Cruises

Departure Date
26 Apr 24
14 Nights

The Diversity Of Central America

Cruise Line Hapag-Lloyd Cruises
Cruise Type Ocean
Ship MS EUROPA 2
Region West Coast US and South America
Departure Port Colón
Destination Port Miami, Florida
Itinerary
Colón, San Blas Islands, Cartagena, Puerto Limón, Belize City, Cozumel, San Miguel de Cozumel, New Orleans, Louisiana, New Orleans, Louisiana, Key West, Florida and Miami, Florida

From £6,600pp

Plus substantial savings from Deluxe Cruises

Departure Date
29 Apr 24
14 Nights

Peru and the Galapagos Islands

Cruise Line Tauck
Cruise Type Ocean
Ship Isabela II
Region South America
Departure Port Santa Cruz Island, Galápagos
Destination Port Baltra Island, Galápagos
Itinerary
Santa Cruz Island, Galápagos, Lima, Cusco, Machu Picchu, Machu Picchu, Cusco, Baltra Island, Galápagos, Santa Cruz Island, Galápagos, San Cristóbal Island, Galápagos, Espanola Island, Floreana Island, Galapagos, Punta Moreno, Isabella Island, Galapagos, El Edén Island, Galápagos, Baltra Island, Galápagos and Baltra Island, Galápagos

From Please Call

Plus substantial savings from Deluxe Cruises

Departure Date
10 May 24
14 Nights

Peru and the Galapagos Islands

Cruise Line Tauck
Cruise Type Ocean
Ship Isabela II
Region South America
Departure Port Santa Cruz Island, Galápagos
Destination Port Baltra Island, Galápagos
Itinerary
Santa Cruz Island, Galápagos, Lima, Cusco, Machu Picchu, Machu Picchu, Cusco, Baltra Island, Galápagos, Santa Cruz Island, Galápagos, San Cristóbal Island, Galápagos, Espanola Island, Floreana Island, Galapagos, Punta Moreno, Isabella Island, Galapagos, El Edén Island, Galápagos, Baltra Island, Galápagos and Baltra Island, Galápagos

From £11,350pp

Plus substantial savings from Deluxe Cruises

Departure Date
21 Jun 24
14 Nights

Peru and the Galapagos Islands

Cruise Line Tauck
Cruise Type Ocean
Ship Isabela II
Region South America
Departure Port Santa Cruz Island, Galápagos
Destination Port Baltra Island, Galápagos
Itinerary
Santa Cruz Island, Galápagos, Lima, Cusco, Machu Picchu, Machu Picchu, Cusco, Baltra Island, Galápagos, Santa Cruz Island, Galápagos, San Cristóbal Island, Galápagos, Espanola Island, Floreana Island, Galapagos, Punta Moreno, Isabella Island, Galapagos, El Edén Island, Galápagos, Baltra Island, Galápagos and Baltra Island, Galápagos

From £11,030pp

Plus substantial savings from Deluxe Cruises

Departure Date
13 Sep 24
14 Nights

Peru and the Galapagos Islands

Cruise Line Tauck
Cruise Type Ocean
Ship Isabela II
Region South America
Departure Port Santa Cruz Island, Galápagos
Destination Port Baltra Island, Galápagos
Itinerary
Santa Cruz Island, Galápagos, Lima, Cusco, Machu Picchu, Machu Picchu, Cusco, Baltra Island, Galápagos, Santa Cruz Island, Galápagos, San Cristóbal Island, Galápagos, Espanola Island, Floreana Island, Galapagos, Punta Moreno, Isabella Island, Galapagos, El Edén Island, Galápagos, Baltra Island, Galápagos and Baltra Island, Galápagos

From £11,030pp

Plus substantial savings from Deluxe Cruises

Departure Date
27 Sep 24
14 Nights

14-Day Wild Guianas To The Amazon Basin

Cruise Line Seabourn
Cruise Type Ocean
Ship Seabourn Venture
Region South America
Departure Port Bridgetown
Destination Port Manaus
Itinerary
Bridgetown, Port-of-Spain, Port-of-Spain, Devil's Island, Macapa, Santarém, Amazon Experience, Amazon Experience, Parintins, Amazon Experience, Amazon Experience and Manaus

From £11,499pp

Plus substantial savings from Deluxe Cruises

Departure Date
07 Oct 24
28 Nights

28-Day Wild Guianas, Amazon & Coast Of Brazil

Cruise Line Seabourn
Cruise Type Ocean
Ship Seabourn Venture
Region South America
Departure Port Bridgetown
Destination Port Rio de Janeiro
Itinerary
Bridgetown, Port-of-Spain, Port-of-Spain, Devil's Island, Macapa, Santarém, Amazon Experience, Amazon Experience, Parintins, Amazon Experience, Amazon Experience, Manaus, Manaus, Amazon Experience, Parintins, Santarém, Amazon Experience, Macapa, Natal and Rio de Janeiro

From Please Call

Plus substantial savings from Deluxe Cruises

Departure Date
07 Oct 24
14 Nights

Peru and the Galapagos Islands

Cruise Line Tauck
Cruise Type Ocean
Ship Isabela II
Region South America
Departure Port Santa Cruz Island, Galápagos
Destination Port Baltra Island, Galápagos
Itinerary
Santa Cruz Island, Galápagos, Lima, Cusco, Machu Picchu, Machu Picchu, Cusco, Baltra Island, Galápagos, Santa Cruz Island, Galápagos, San Cristóbal Island, Galápagos, Espanola Island, Floreana Island, Galapagos, Punta Moreno, Isabella Island, Galapagos, El Edén Island, Galápagos, Baltra Island, Galápagos and Baltra Island, Galápagos

From £11,030pp

Plus substantial savings from Deluxe Cruises

Departure Date
11 Oct 24
14 Nights

14-Day Amazon Delta & Coast Of Brazil

Cruise Line Seabourn
Cruise Type Ocean
Ship Seabourn Venture
Region South America
Departure Port Manaus
Destination Port Rio de Janeiro
Itinerary
Manaus, Manaus, Amazon Experience, Parintins, Santarém, Amazon Experience, Macapa, Natal and Rio de Janeiro

From £7,899pp

Plus substantial savings from Deluxe Cruises

Departure Date
21 Oct 24
7 Nights

Vast Ocean, Deep Relaxation

Cruise Line Hapag-Lloyd Cruises
Cruise Type Ocean
Ship Hanseatic Inspiration
Region South America
Departure Port Boston, Massachusetts
Destination Port Colón
Itinerary
Boston, Massachusetts and Colón

From £2,432pp

Plus substantial savings from Deluxe Cruises

Departure Date
28 Oct 24